Tantalum Cluster Derivatization Kit
Tantalum Bromide Clusters are used for the preparation of heavy-atom
derivatives for structure determination of biological macromolecules by X-ray analysis.
This electron-rich compound can be employed in single and multiple isomorphous replacement
(SIR and MIR) experiments in order to induce measurable changes of the diffraction
intensities required for phase calculation.
The cluster also contains two strong anomalous scatterers suitable
for multiple anomalous diffraction (MAD) experiments.
Tantalum bromide clusters have been successfully employed in
several structural studies because of their high electron-density,
solubility in aqueous solutions and stability over a wide pH range.
Each kit contains 6 - 1 mg solid aliquots of hexatantalum tetradecabromide.