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Lanthanide phasing compound (ref.: CSM002-0002A)

Derivatives are obtained, either by soaking or by co-crystallization, into crystals of biological macromolecules. The crystal derivatives thus obtained can be used to solve the structure of biological macromolecules by using structure-determination methods taking advantage of the strong anomalous signal of lanthanides in its LIII absorption edge or with radiation from a lab X-ray source.

Full documentation is available here.

A list of publications related to the use of these complexes is available here.

Information on Gd-HPDO3A molecule:
Gd-HPDO3A pdb file

Authors publishing results thanks to these compounds are welcome to cite the following paper:
Girard E, Stelter M, Vicat J, Kahn R, Acta Cryst. D59 (2003), 1914-1922

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